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About KMS About Message from the Dean Campus Outline Outline Organization chart History Kochi Medical School Outline Facilities Facility list kochi Medical School Hospital Center of Medical Information Science Center for Innovative and Translational Medicine Center for Photodynamic Medicine Center for Medical Education Development Library and Imformation Technology, Medical School Branch Campus life Campus life International Exchanges International Exchanges To Prospective International Students Overseas partner schools Health Service Center,Medical School Branch(Oko Campus) Access Education Education Medical department Medical department Medical Course Medical Course Neurobiology and Anatomy Pathology Physiology Cardiovascular Control Biochemistry Functional Genomics Molecular Biophysics Pharmacology Microbiology and Infection Parasitology Immunology Legal Medicine Environmental Medicine Public Health Hospital Administration Section Liaison Healthcare Engineering Section Laboratory Medicine Diagnostic and Interventional Radiology Radiation Oncology Anesthesiology and Intensive Care Medicine Gastroenterology and Hepatology Endocrinology, Metabolism & Nephrology Respiratory Medicine and Allergology Hematology Cardiology and Geriatrics Medical Oncology Neurology Clinical Infectious Diseases Dermatology Pediatrics Obstetrics and Gynecology Neuropsychiatry Gastroenterological Surgery Breast Surgical Oncology Pediatric Surgery Cardiovascular Surgery General Thoracic Surgery Clinical Oncology and Minimally Invasive Surgery Plastic and Reconstructive Surgery Orthopaedic Surgery Urology Ophthalmology Otolaryngology, Head and Neck Surgery Neurosurgery Oral and Maxillofacial Surgery Disaster and Emergency Medicine Family Medicine Child and Adolescent Psychiatry Medical Virtual Reality Crisis Management Medicine Clinical Epidemiology Kochi-Umajimura Yuzu Health Research Course YAMAKIN Next Generation Dental Medical Development Lecture Molecular and Cellular Biology Nursing Course Graduate School Graduate School Medical Science(Master's Course) Medical Science(Master's Course) Medical Science Course Public Health Course Healthcare Innovation Course Nursing Science(Master's Course) Medicine(Doctoral Course) Medicine(Doctoral Course) Life Science Course Clinical Science Course Information Healthcare Science Course Neurology/Psychiatry in Child and Adolescence Course MD-PhD Course Ocean and Medicine Course About KMS A Message from the Dean Campus map Outline Organization chart History Kochi Medical School Outline Facilities Kochi Medical School Hospital Center of Medical Information Science Center for Innovative and Translational Medicine Center for Photodynamic Medicine Center for Medical Education Development Library and Imformation Technology, Medical School Branch Campus life International Exchanges To Prospective International Students Overseas partner schools Health Service Center,Medical School Branch(Oko Campus) Access Education Medical department Medical Course Neurobiology and Anatomy Pathology Physiology Cardiovascular Control Biochemistry Functional Genomics Molecular Biophysics Pharmacology Microbiology and Infection Parasitology Immunology Legal Medicine Environmental Medicine Public Health Hospital Administration Section Liaison Healthcare Engineering Section Laboratory Medicine Diagnostic and Interventional Radiology Radiation Oncology Anesthesiology and Intensive Care Medicine Gastroenterology and Hepatology Endocrinology, Metabolism & Nephrology Respiratory Medicine and Allergology Hematology Cardiology and Geriatrics Medical Oncology Neurology Clinical Infectious Diseases Dermatology Pediatrics Obstetrics and Gynecology Neuropsychiatry Gastroenterological Surgery Breast Surgical Oncology Pediatric Surgery Cardiovascular Surgery General Thoracic Surgery Clinical Oncology and Minimally Invasive Surgery Plastic and Reconstructive Surgery Orthopaedic Surgery Urology Ophthalmology Otolaryngology, Head and Neck Surgery Neurosurgery Oral and Maxillofacial Surgery Disaster and Emergency Medicine Family Medicine Child and Adolescent Psychiatry Medical Virtual Reality Crisis Management Medicine Clinical Epidemiology Kochi-Umajimura Yuzu Health Research Course YAMAKIN Next Generation Dental Medical Development Lecture Molecular and Cellular Biology Nursing Course Graduate School Medical Science Program (Master’s Course) Medical Science Course Public Health Course Healthcare Innovation Course Nursing Science(Master's Course) Medicine(Doctoral Course) Life Science Course Clinical Science Course Information Healthcare Science Course Neurology/Psychiatry in Child and Adolescence Course MD-PhD Course Ocean and Medicine Course Search Access Language Japanese English EDUCATION Department of Microbiology and Infection HOME Education About medical school Medical Course Department of Microbiology and Infection Overview Cancer is the leading cause of human death worldwide. A significant portion of human cancer cases, an estimated 20%–30%, attributed to an infectious etiology. So far, seven human tumor viruses are known to be associated with development and pathogenesis of cancers. The viruses include Epstein-Barr virus (EBV), human T-cell leukemia virus 1 (HTLV-1), human papillomavirus (HPV), hepatitis B (HBV) and C viruses (HCV), human herpesvirus 8 (HHV-8) that is also called Kaposi’s sarcoma herpesvirus (KSHV), and Merkel cell polyomavirus (MCPyV). We aim to define the oncogenic mechanism and pathogenesis of diseases caused by these viruses, especially EBV,HPV and MCPyV. Research areas 1) Viruses and Cancer Several viruses are linked with cancers in humans. MCPyV was discovered in 2008 from a rare and aggressive type of skin cancer called Merkel cell carcinoma. We search for MCPyV-related disorders other than MCC. We also study how people become infected with MCPyV and how MCPyV becomes pathogenic, although this virus has been found in a number of places in body, including normal skin, without any symptoms. 2) Hematological malignancies caused by microbiological pathogens A variety of microbiological pathogens are associated with pathogenesis of hematological malignancies. For examples, EBV is the causative factor of various types of non-Hodgkin lymphomas including Burkitt’s lymphoma, pyothorax-associated lymphoma (PAL), extranodal NK/T cell lymphoma (nasal type) and diffuse large B-cell lymphoma of the elderly. MALT (mucosa-associated lymphoid tissue) lymphoma is also associated with chronic gastritis caused by Helicobacter pylori. We study molecular mechanism of the infection-related lymphomas by defining both the host cellular and viral (bacterial) gene expression profiles. Staff Department Name Professor Masanori Daibata Assistant Professor Tomonori Higuchi Assistant Lecturer Yumiko Hashida Kochi Medical SchoolDepartment of Microbiology and Infection http://www.kochi-u.ac.jp/kms/ff_mcrbi/ TEL:+81-88-880-2323 Kochi Medical School／ Graduate School Medical Science Program, Nursing Science Program, Medicine Program Kohasu,Oko-cho,Nankoku-shi,Kochi 783-8505, JAPAN Contact About KMS Message from the Dean Campus map Outline Campus life Access Education Medical department Nursing Course Graduate School Kochi Medical School at rights reserved.