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順天堂大学 大学院医学研究科 難病の診断と治療研究センターCenter of Sportologyセンターについてメンバー研究部門業績アクセス難治性疾患・再生医療実用化研究室業績難治性疾患・再生医療実用化研究室業績一覧【2022】原著 Tanaka R, Fujimura S, Kado M, Fukuta T, Arita K, Hirano-Ito R, Mita T, Watada H, Kato Y, Miayuchi K, Mizuno H Phase I/IIa feasibility trial of autologous quality- and quantity-cultured peripheral blood mononuclear cell therapy for non-healing extremity ulcers. Stem Cells Trasl Med 11: 146-158, 2022Jiang S, Ito-Hirano R, Nishikai-Shen T, Fujimura S, Mizuno H and Tanaka R Effect of MNCQQ cells on migration of human dermal fibroblast in diabetic condition. Biomedicines 10: 2544, 2022Tobita M, Masubuchi Y, Ogata Y, Mitani A, Kikuchi T, Toriumi T, Raudales JLM, Mizuno H, Suzuki Y, Wakana K, Yoneda H, Kamijo R, Kino-oka M, Morio T, Okada K, Murakami S and Honda M Study protocol for periodontal tissue regeneration with a mixture of autologous adipose-derived stem cells and platelet rich plasma: A multicenter, randomized, open-label clinical trial. Regener Ther 21: 436-441, 2022【2021】原著 Nishikai-Yan ST, Kado M, Hagiwara H, Fujimura S, Mizuno H, Tanaka R MMP9 secreted from mononuclear cell quality and quantity culture mediates STAT3 phosphorylation and fibroblast migration in wounds. Regen Ther 18: 464-471, 2021Geeroms M, Fujimura S, Aiba E, Orgun D, Arita K, Kitamura R, Senda D, Mizuno H, Hamdi M, Tanaka R Quality and quantity-cultured human mononuclear cells improve human fat graft vascularization and survival in an in vivo murine experimental model. Plast Reconstr Surg 147: 373-385, 2021Tanaka R, Ito-Hirano R, Fujimura S, Arita K, Hagiwara H, Mita T, Itoh M, Kawaji H, Ogawa T, Watada H, Masuda H, Asahara T, Mizuno HEx vivo conditioning of peripheral blood mononuclear cells of diabetic patients promotes vasculogenic wound healing.Stem Cells Transl Med, 10: 895-909, 2021.【2020】原著 水野博司、山下理絵、宮田成章、林　寛子 特定細胞加工物および細胞増殖因子を用いた注入療法の現状調査 日本美容外科学会会報 42: 19-26, 2020【2019】原著 Geeroms M, Hamdi M, Hirano R, Hagiwara H, Fujimura S, Mizuno H and Tanaka R Quality and quantity cultured murine endothelial progenitor cells increase vascularization and decrease fibrosis in the fat graft Plast Reconstr Surg 143: 744e-455e, 2019Tanaka R, Umeyama Y, Hagiwara H, Ito-Hirano R, Fujimura S, Mizuno H, Ogawa R. Keloid patients have higher peripheral blood endothelial progenitor cell counts and CD34+ cells with normal vasculogenic and angiogenic function that　overexpress vascular endothelial growth factor and interleukin-8. Int J Dermatol 58: 1398-1405, 2019総説 藤村　聡、田中里佳 順天堂大学における細胞調製施設運営の課題と現状 クリーンテクノロジー 29: 5-8, 2019水野博司 再生医療法と美容医療 「PEPARS」 No. 147　美容医療の安全管理とトラブルシューティング－Ⅱ安全な美容医療を行うための必須事項 編集：大慈弥裕之　2019; 147-155　全日本病院出版会著書 水野博司 脂肪注入・移植における脂肪精製・処理 「脂肪注入移植術」　編集：淺野裕子、関堂　充　2019; pp14-20　克誠堂出版【2018】原著 Tanaka R, Masuda H, Fujimura S, Ito-Hirano R, Arita K, Kakinuma Y, Hagiwara H, Kado M, Hayashi A, Mita T, Ogawa T, Watada H, Mizuno H, Sawada N and Asahara T Quality-quantity control culture enhances vasculogenesis and wound healing efficacy of human diabetic peripheral blood CD 34+ cells Stem Cells Transl Med 7: 428-438, 2018Kado M, Tanaka R, Arita K, Okada K, Hirano R, Fujimura S and Mizuno H Human peripheral blood mononuclear cells enriched in endothelial progenitor cells via quality and quantity controlled culture accelerate vascularization and wound healing in a porcine wound model Cell Transplant 27: 1068-1079, 2018Hagiwara H, Higashibata A, Ogawa S, Kanazawa S, Mizuno H and Tanaka R Effectiveness of endothelial progenitor cell culture under microgravity for improved angiogenic potential Sci Rep 8: 14239, 2018Ohtake T, Kobayashi S, Mochida Y, Ishioka K, Moriya H, Hidaka S, Matsuura R,　Sumida M, Katagiri D, Noiri E, Slavin S, Mizuno H and Tanaka R Human peripheral blood mononuclear cells incubated in vasculogenic conditioning medium dramatically improve ischemia/reperfusion acute kidney injury in mice. Cell Transplantation 27(3) 520–530, 2018総説 Tajima S, Tobita M and Mizuno H Current status of bone regeneration using adipose-derived stem cells Histol Histopathol 33: 619-627, 2018福田太郎、田中里佳 難治性四肢潰瘍に対する血管再生治療 血管外科 37(1): 110-114, 2018田中里佳 再生医療による創傷治癒の未来 WOC Nursing 6(7):26-34, 2018藤村　聡、田中里佳 難治性四肢潰瘍患者を対象とした次世代の血管・組織再生治療 内分泌・糖尿病・代謝内科 47(1)：18-23, 2018著書 Tajima S, Tobita M and Mizuno H Bone regeneration with a combination of adipose-derived stem cells and platelet-rich plasma In「Adipose Derived Stem Cells: Methods and Protocols, Second Edition」Editors: Bunnell BA and Gimble JM 2018; pp261-272, Springer, New York, NY【2017】Luo L, Tanaka R, Kanazawa S, Lu F, Yokomizo T and Mizuno H A synthetic BLT2 agonist accelerates the cutaneous wound healing process in diabetic rats by indirect stimulation of fibroblasts and direct stimulation of keratinocytes J Diabetes Complications 31: 13-20, 2017Shingyochi Y, Kanazawa S, Tajima S, Tanaka R, Mizuno H and Tobita M A low-level carbon dioxide laser promotes fibroblast proliferation and migration through activation of Akt, ERK, and JNK PLOS ONE 12: e168937, 2017Nishikai-Yan Shen T, Kanazawa S, Kado M, Okada K, Luo L, Hayashi A, Mizuno H and Tanaka R Interleukin-6 stimulates Akt and p38 MAPK phosphorylation and fibroblast migration in non-diabetic but not diabetic mice PLOS ONE 23; 12: e0178232, 2017Mifuji K, Ishikawa M, Kamei N, Tanaka R, Arita K, Mizuno H, Asahara T, Adachi N and Ochi M Angiogenic conditioning of peripheral blood mononuclear cells promotes fracture healing Bone Joint Res 6: 489-498, 2017Fukui T, Kawaguchi A, Takekoshi S, Miyasaka M, Sumiyoshi H and Tanaka R Liposome-encapsulated hemoglobin accelerates skin wound healing in diabetic dB/dB mice Artif Organs 41: 319-326, 2017Ohtake T, Kobayashi S, Mochida Y, Ishioka K, Moriya H, Hidaka S, Matsuura R, Sumida M, Katagiri D, Noiri E, Slavin S, Mizuno H and Tanaka R Human peripheral blood mononuclear cells incubated in vasculogenic conditioning medium dramatically improve ischemia/reperfusion acute kidney injury in mice Cell Transplant 27: 520-530, 2018総説 Orgun D and Mizuno H Multipotency and secretome: the mechanisms behind the regenerative potential of adipose-derived stem cells Plast Aesthet Res 4: 32-40, 2017田中里佳 血管幹細胞を用いた組織再生医療 日本形成外科学会会誌 37: 173-179, 2017藤村　聡、田中里佳 患者まで届いている再生医療―難治性四肢潰瘍患者に対する次世代の血管・組織再生治療 再生医療 16: 26-31, 2017田中里佳 末梢血単核球生体外培養増幅法（QQc法）を用いた血管再生治療 メディカル・サイエンス・ダイジェスト 43： 2-3, 2017田中里佳 再生医療を利用した先進的創傷治療 PEPARS 126: 30-37, 2017著書 Mizuno H, Tobita M, Ogawa R, Orbay H, Fujimura J, Ono S, Kakudo N, Kusumoto K and Hyakusoku H Adipose-derived stem cells in regenerative medicine In「Principle of gender-specific medicine」Editor: Legato MJ 2017; pp459-479, Elsevier, San Diego, CATajima S, Tobita M and Mizuno H Bone regeneration with a combination of adipose-derived stem cells and platelet-rich plasma In「Adipose Derived Stem Cells: Methods and Protocols, Second Edition」Editors: Bunnell BA and Gimble JM 2018; pp261-272, Springer, New York, NY田中里佳 再生医療　 「フットケア診療の手引き」編集：日本フットケア学会、医学書院 204-208, 2017【2016】原著 Horikoshi-Ishihara H, Tobita M, Tajima S, Tanaka R, Oshita T, Tabata Y and Mizuno H Co-administration of adipose-derived stem cells and control-released basic fibroblast growth factor facilitates angiogenesis in a murine ischemic hind limb model J Vasc Surg 64: 1825-1834, 2016Huang C, Orbay H, Tobita M, Miyamoto M, Tabata Y, Hyakusoku H and Mizuno H Pro-apoptotic effect of control-released basic fibroblast growth factor on skin wound healing in a diabetic mouse model Wound Repair Regen 24: 65-74, 2016Oshita T, Tobita M, Tajima S and Mizuno H Adipose-derived stem cells improve collagenase-induced tendinopathy in a rat model Am J Sports Med 44: 1983-1989, 2016著書 Mizuno H, Tobita M, Orbay H, Uysal AC and Lu F Adipose-derived stem cells as a novel tool for future regenerative medicine In「Stem Cells and Cancer Stem Cells」 Editor: Hayat MA, Springer, New York, NY in pressTajima S, Tobita M and Mizuno H Bone regeneration with a combination of adipose-derived stem cells and platelet-rich plasma In「Adipose Derived Stem Cells: Methods and Protocols, Second Edition」 Editors: Bunnell BA and Gimble JM, Springer, New York, NY業績ゲノム医学研究・難治性疾患実用化研究室難治性疾患・再生医療実用化研究室難病の診断と治療研究センターIntractable Disease Research Center センターについて メンバー 研究部門 業績 アクセス プライバシーポリシー 〒113-8421　東京都文京区本郷2-1‐1 Copyright © JUNTENDO All rights reserved.